article · Food Chemistry Advances
Ginger is a widely used herb recognised for its broad pharmacological characteristics. This investigation evaluated the physicochemical qualities, phytochemical composition, and antibacterial potential of Zingiber officinale extracts. Laboratory testing confirmed the presence of various phytochemicals across the extracts, though steroids and cardiac glycosides were absent from the chloroform and n-hexane preparations. Tested against several bacterial pathogens, including Porphyromonas gingivalis, Proteus mirabilis, Streptococcus pyogenes, Salmonella, Mycobacterium, and Enterobacterium, the extracts demonstrated clear inhibitory effects at concentrations of 50, 100, and 200 mg/mL. Among the tested preparations, the ethanolic extracts delivered superior antibacterial inhibition at the highest tested dose of 200 mg/mL against all the examined organisms. These outcomes confirm that ginger rhizomes possess bioactive phytochemicals capable of inhibiting disease-causing bacteria.
Bacterial infections remain a widespread health concern, increasing the demand for effective natural antimicrobial agents. By confirming that ginger extracts can suppress multiple pathogenic bacteria such as Salmonella and Streptococcus pyogenes, this research highlights the scientific basis for using botanical compounds in combating harmful microbes and supporting ongoing searches for plant-derived treatments.
This laboratory evaluation provides early-stage evidence that ginger extracts, particularly ethanolic formulations, possess antibacterial properties against diverse pathogens. Potential future users could include pharmaceutical and natural health product developers seeking botanical active ingredients. However, the work remains at an early laboratory screening stage, and substantial further testing, formulation, and safety evaluation would be required before any commercial antimicrobial application is possible.
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Ginger (Zingiber officinale) is a promising herb utilized all over the world beacuseof its extensive pharmacological properties. This study aims to evaluate the physicochemical, phytochemicals and anti-bacterial potential of Zingiber officinale. The extracts showed the existence of phytochemicals, although the chloroform and n-hexane extracts showed absence of steroids and cardiac glycosides. At 50, 100, and 200 mg/mL doses, extracts from Zingiber officinale inhibited the pathogens (Porphyromonas gingivalis, Proteus mirabilis, Streptococcus pyogenes, Salmonella, Mycobacterium, and Enterobacterium) that were being tested. The antibacterial potentials of Zingiber officinale were thus revealed in this study and are supported by biological processes. The ethanolic extracts showed superior inhibition at 200 mg/mL against Porphyromonas gingivalis, Proteus mirabilis, Streptococcus pyogenes, Salmonella, Mycobacterium, and Enterobacterium. The findings in this current research show that ginger contains phytochemicals that exert antibacterial properties.
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DOI: 10.1016/j.focha.2024.100625
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