article · Food Wellness
Dietary sources such as nuts, seeds, legumes, and seafood have been shown to enhance endothelial function by promoting NO production. Flavonoids, naturally occurring bioactive compounds found in fruits, vegetables, tea, and cocoa, possess antioxidant, anti-inflammatory, and vasodilatory properties that contribute to improved vascular health. Epidemiological and clinical studies suggest that higher dietary intake of flavonoids, particularly anthocyanins, flavanones, and flavanols, is associated with a reduced risk of erectile dysfunction. The combined effects of L-arginine and flavonoids may enhance erectile function by improving endothelial function, increasing nitric oxide bioavailability, reducing oxidative stress, and promoting blood flow to the penis. This nutritional approach may serve as a complementary or alternative strategy to conventional therapies, particularly for individuals with mild to moderate ED or those seeking holistic management options. However, further well-designed randomized controlled trials are needed to establish optimal dietary intake levels and clarify the long-term effects of these compounds on erectile and vascular health.
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DOI: 10.1016/j.foodw.2026.100045
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