When the Cecum Hides a Sarcoma: A Rare Case of Undifferentiated Malignancy

Abstract

Primary undifferentiated sarcoma of the cecum is an exceptionally rare and aggressive mesenchymal tumor, often difficult to diagnose due to its nonspecific presentation and overlap with more common colonic malignancies. We report the case of a 66-year-old patient presenting with right iliac fossa pain and bowel transit disturbances. Imaging revealed a large cecal mass without distant metastasis. The patient underwent surgical resection. Histopathological and immunohistochemical examination confirmed a primary undifferentiated sarcoma of the cecum. Postoperative management was discussed in a multidisciplinary setting. Through this case, we highlight the diagnostic challenges and therapeutic considerations of this rare entity.