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review · European Journal of Clinical Investigation

When less is more: The association between the expression of polymorphic <scp>CYPs</scp> and <scp>AFB1</scp>‐induced <scp>HCC</scp>

202413 citationsOpen accessGerman University in Cairo

Abstract

Polymorphic variants of CYP enzymes have a functional impact on the susceptibility to AFB1-induced HCC. Outlining such variation and their implications may provide deeper insights into approaching HCC in a more personalized manner for guiding future risk-assessment, diagnosis, and treatment.

Research topics

  • Pharmacogenetics and Drug Metabolism
  • PI3K/AKT/mTOR signaling in cancer
  • Genomics, phytochemicals, and oxidative stress

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DOI: 10.1111/eci.14297

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