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article · Kidney International Reports

WCN24-1697 INTERLEUKIN-35 AS A BIOMARKER OF RENAL INVOLVEMENT IN SYSTEMIC LUPUS ERYTHEMATOSUS SINGLE-CENTRED STUDY

2024Open accessSuez Canal University

Abstract

Lupus nephritis (LN) is a common complication of systemic lupus erythematosus (SLE) diagnosed via histopathology of renal biopsy. Investigating surrogate markers to predict renal involvement in LN is a safe non-invasive method to be studied. One of those markers is Interleukin 35 (IL-35) which has an immunosuppressive and anti-inflammatory role in many autoimmune diseases. However, its role in LN still needs to be elucidated. This study aimed to evaluate serum levels of IL-35 in SLE patients with and without LN as a biomarker of renal involvement.

Research topics

  • Systemic Lupus Erythematosus Research
  • Atherosclerosis and Cardiovascular Diseases
  • Systemic Sclerosis and Related Diseases

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DOI: 10.1016/j.ekir.2024.02.349

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