article · Pharmaceutical Biology
CONTEXT: belonging to the family: Oscillatoriaceae, are rich sources of bioactive compounds with potential anticancer properties. OBJECTIVE: and evaluate their anticancer activity against breast and liver cancer cell lines. MATERIALS AND METHODS: was collected and authenticated using 16S rRNA sequencing. The ethanolic extract was analyzed using LC-QTOF-MS/MS to identify the potential bioactive metabolites. Network pharmacology analysis was employed to predict the potential targets of these compounds. The crude extract was fractionated, and the fractions were screened for the anticancer activity against MCF-7 and HepG2 cell lines. RESULTS: values, 59.63 ± 7.1 and 149.23 ± 0.9 µg/mL, respectively. DISCUSSION AND CONCLUSION: as a source of novel anticancer compounds. Further investigation of the bioactive compounds in Fractions 1 and 2 may lead to the discovery of promising anticancer agents.
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DOI: 10.1080/13880209.2025.2534573
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