article · Tanzania Medical Journal
Pilomatrixoma is a rare and benign superficial skin tumour that originates from hair follicle matrix cells, though it can occasionally turn malignant. Because it is frequently misdiagnosed during clinical evaluation, accurate identification is critical. A clinical case involved a nineteen-year-old male who had an ulcerated, painless swelling on the medial section of his right upper eyelid for two years. The lesion was initially suspected to be a keratoacanthoma and was later clinically diagnosed as a basal cell carcinoma. Following complete surgical excision, a histopathological examination confirmed the growth to be a pilomatrixoma. Complete surgical removal typically provides a curative outcome. This case demonstrates the persistent challenge of accurately identifying pilomatrixomas purely through clinical assessment.
Pilomatrixomas can visually mimic other skin conditions, including malignant cancers such as basal cell carcinoma. Sharing detailed diagnostic journeys helps clinicians recognise atypical presentations, such as ulcerated eyelid tumours. This awareness ensures patients receive appropriate histopathological evaluations and definitive curative surgical treatments rather than inappropriate therapies.
The abstract does not indicate an application pathway, as it presents an individual clinical case report focused on surgical excision and histopathological diagnosis.
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Pilomatrixoma is a rare superficial benign skin tumor arising from the hair follicle matrix cells. Pilomatrixoma can occasionally become malignant. Complete surgical excision is often curative. It is often clinically misdiagnosed, hence the reason to share this case. We report a case of a 19-year-old man who presented with an ulcerated non-painful swelling involving the medial part of the right upper eyelid for two years. It was initially clinically diagnosed as keratoacanthoma and later basal cell carcinoma. However, histopathological examination after complete surgical excision revealed features of pilomatrixoma. This report highlights that pilomatrixoma may be misdiagnosed in clinical practice.
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DOI: 10.4314/e66vja86
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