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Toxicological evaluation and preliminary phytochemical characterisation of a Nigerian <i>Cannabis sativa</i> chemovar.

Abstract

Objectives: . Materials and Methods: The plant samples were air-dried, powdered, extracted with ethanol, and characterized (phytochemical screening, Fourier Transformed Infrared Spectroscopy (FTIR), and Gas Chromatography-Mass Spectrometry (GC-MS)). Acute and subacute toxicity tests were done following Organisation for Economic Co-operation and Development (OECD) protocols. Results: 0.05) higher in the 250 mg/kg group. Also, we observed mild to moderate necrosis in the excised pancreas and liver, and mild tubular changes in the kidney. Conclusion: may be considered safe following oral consumption.

Research topics

  • Cannabis and Cannabinoid Research
  • Hibiscus Plant Research Studies
  • African Botany and Ecology Studies

Sustainable Development Goals

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DOI: 10.22038/ijbms.2025.85494.18494

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