article · Malaria Journal

Therapeutic efficacy of generic artemether–lumefantrine in the treatment of uncomplicated malaria in Ghana: assessing anti-malarial efficacy amidst pharmacogenetic variations

Nicholas Ekow Thomford
Robert Peter Biney
Samuel Badu Nyarko
Richmond Owusu Ateko
Charné Dixon
Martins Ekor
Tracy Kellermann
George B. Kyei

20243 citationsOpen accessStellenbosch University

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Abstract

The study findings show that CYP2B6 and CYP3A5 pharmacogenetic variations may lead to higher plasma exposure of AL metabolites.

Research topics

Malaria Research and Control
Computational Drug Discovery Methods
Pharmacogenetics and Drug Metabolism

Sustainable Development Goals

Good Health and Well-being

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DOI: 10.1186/s12936-024-04930-1

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