The Significance of High-Sensitivity Cardiac Troponin T with Left Ventricular Strain in Heart Failure with Preserved Ejection Fraction

Abstract

Background: There is not enough information available at this time to determine if patients with stable heart failure and preserved ejection fraction also experience higher left ventricular strain and high-sensitivity troponin, which are associated with a worsening of the condition. Aim: To predict and early diagnose left ventricular dysfunction in patients with heart failure with preserved ejection fraction Methods: This case control study was conducted on 48 subjects diagnosed with HFpEF, at Cardiology Department, Faculty of Medicine, Zagazig University. The patients were divided into 2 equal groups: case group (n=24): included patients diagnosed with HFpEF with diastolic dysfunction and control group (n=24): included healthy individuals. High-sensitivity cardiac troponin T and left ventricular strain were assessed in all subjects. Results: High sensitivity cardiac troponin T, GLS, GDSIVR, GDSE, SRE, E/SRE and SRIVR were considerably greater in the cases group as opposed to the control group (P<0.05). Conclusion: In comparison to normal controls, our investigation revealed that HFpEF patients with diastolic dysfunction had significantly higher hs-cTnT levels, more severe anomalies in left ventricular strain, and more advanced diastolic dysfunction.