The Role of Endoscopic Narrow Band Imaging (NbI) in Diagnosis of Helicobacter Pylori Gastritis

Abstract

Background: Helicobacter pylori [H. pylori] is a predominant cause of chronic gastritis that can lead to gastric cancer if left untreated. Currently, endoscopy and histology are the gold standard tests for the diagnosis of H. pylori gastritis. Recently, studies have shown the utility of narrow-band imaging [NBI] in predicting H. pylori gastritis. Thus, this study aimed to determine the diagnostic accuracy of NBI in prediction of H. pylori gastritis.Patients and Methods: This was a prospective cohort hospital based study. It was conducted on 50 consecutive adult patients attending the endoscopy unit of the Hepatology and gastroenterology department of the National Liver Institute, Menoufia University. Each patient underwent upper endoscopy, NBI studies followed by biopsies from the antrum and fundus of the stomach. Analysis was performed for the types of NBI pattern predicting H. pylori gastritis.Results: The abnormal NBI pattern of the gastric mucosa on endoscopy was significantly linked to H. pylori infection [p 0.002]. In addition, NBI yielded an excellent diagnostic accuracy. The sensitivity was 86.36, and specificity was 66.67, PPV was 95.00, NPV was 40.00, and the accuracy was 84%..Conclusion: NBI findings by endoscopy had an excellent diagnostic accuracy for identification of H. pylori gastritis. However, future multicenter large-scale studies are recommended to validate our results. In addition, future studies are required to study the site-specific biopsy guided by NBI of abnormal mucosa