THE ROLE OF AFRICAN UNIVERSITIES AND RESEARCH INSTITUTIONS IN ADVANCING SICKLE CELL DISEASE INNOVATION: A PERSPECTIVE

Abstract

Sickle Cell Disease (SCD) remains one of the most prevalent genetic disorders in Africa, contributing significantly to morbidity and mortality across the continent. African universities and research institutions have emerged as key players in advancing innovation to combat this burden through focused research, capacity building, and policy advocacy. Their localized efforts are essential in addressing the unique genetic, environmental, and socio-economic factors influencing SCD in African populations. These institutions have made substantial contributions in understanding the molecular genetics of SCD, conducting epidemiological studies, and leading clinical trials tailored to local contexts. Additionally, they play a crucial role in training healthcare professionals and researchers, thereby strengthening the continent’s capacity to provide effective care and develop novel therapeutic approaches. Collaborative research networks and dedicated centers further accelerate innovation, facilitating the translation of scientific discoveries into practical interventions such as newborn screening and point-of-care diagnostics. Peer Review History: Received 4 December 2025; Reviewed 17 January 2026; Accepted 15 February; Available online 15 March 2026 Academic Editor: Dr. Muhammad Zahid Iqbal, AIMST University, Malaysia, drmmziqbal@gmail.com Reviewers: Dr. Vanina Doris Edo’o, University of Yaounde I, Yaounde, Cameroun, vanina_edoo@yahoo.com Dr. Wilman Ismael Carrillo Terán, Technical University of Ambato Avda, Ecuador, wilmanct@gmail.com