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article · Journal of Antimicrobial Chemotherapy

The impact of alcohol and illicit substance use on the pharmacokinetics of first-line TB drugs

20245 citationsOpen accessStellenbosch University

Abstract

No clinically relevant effect of alcohol use was observed on the pharmacokinetics of first-line TB drugs, suggesting that poor treatment outcome is unlikely due to pharmacokinetic alterations. That methaqualone reduced rifampicin means dose adjustment may be beneficial.

Research topics

  • Tuberculosis Research and Epidemiology
  • Pharmacological Effects and Toxicity Studies
  • Epilepsy research and treatment

Sustainable Development Goals

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DOI: 10.1093/jac/dkae206

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