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article · Journal of Biomolecular Structure and Dynamics

The anticancer and anti-inflammatory activity screening of pyridazinone-based analogs against human epidermoid skin cancer with detailed mechanistic analyses

202311 citationsSuez University

Abstract

data. In conclusion, the pyridazine moieties with piperdine, naphthayl, and pyridine have pharmacological activities against skin cancer epidermoid by triggering action in inhibition of the proliferation and progression with an up-regulated apoptotic mechanism that evades the emergence of cisplatin resistance among different cancer cells.Communicated by Ramaswamy H. Sarma.

Research topics

  • Synthesis and biological activity
  • Synthesis and Characterization of Heterocyclic Compounds
  • Cancer therapeutics and mechanisms

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DOI: 10.1080/07391102.2023.2273985

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