article · Current Medicinal Chemistry

Synthesis of Bis-thiazoles Tethered 1,4-Dihydropyridine and Pyridine Linkers via Simple Oxidation and their Molecular Docking as VEGFR -TK Inhibitors

Jehan Y. Al‐Humaidi
Magdi E. A. Zaki
Sayed M. Riyadh
Basant Farag
Tariq Z. Abolibda
Sobhi M. Gomha

202411 citationsZagazig University

Abstract

Additionally, the compounds exhibiting the highest activity were assessed for their potential anticancer effects against HepG-2, MCF-7, and WI-38 cells, and the outcomes demonstrated encouraging activity against cancer.

Research topics

Synthesis and biological activity
Synthesis and Characterization of Heterocyclic Compounds
Synthesis of Tetrazole Derivatives

Sustainable Development Goals

12Responsible Consumption and Production

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DOI: 10.2174/0109298673266044231002071238

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