article · BMC Chemistry
This is the first reported chromatographic method enabling simultaneous quantification of COL and DEX in pharmaceutical and plasma matrices together with a comprehensive, multi-tool sustainability assessment (including VIGI and EPPI). The method's short run time, high sensitivity, and favorable sustainability scores support its application in routine quality control and preclinical pharmacokinetic studies.
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DOI: 10.1186/s13065-026-01723-2
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