Subarachnoid haemorrhage in a newly diagnosed Chronic Myelogenous Leukemia patient: A diagnostic challenge

Abstract

Chronic Myelogenous Leukemia (CML) is a myeloproliferative neoplasm with a prevalence of 1 to 2 cases per 100,000 adult population. In chronic myelogenous leukemia (CML), central nervous system (CNS) manifestations are reported in the advanced phase of the disease due to leukostasis, thrombosis, bleeding, infection, and CNS infiltration. However, CNS manifestations are uncommon in the chronic phase (CP) of CML, and an alternate diagnosis should be considered for symptomatic patients. We report a ruptured aneurysmal subarachnoid hemorrhage (SAH) as an initial presentation in a previously undetected CML patient.