article · PLoS neglected tropical diseases

Simplified molecular diagnosis of visceral leishmaniasis: Laboratory evaluation of miniature direct-on-blood PCR nucleic acid lateral flow immunoassay

Norbert van Dijk
José Carlos Solana
Carmen Chicharro
Dawit Gebreegziabiher Hagos
Dawit Wolday
Eugenia Carrillo
Sophia Ajala
David Kiptanui
Edwin Abner
D Huggins
Henk D. F. H. Schallig

202410 citationsOpen accessMekelle University

Abstract

Mini-dbPCR-NALFIA is a promising tool for simplified molecular diagnosis of VL and follow-up of treated patients in blood samples. Future studies should evaluate its use in endemic, resource-limited settings, where mini-dbPCR-NALFIA may provide an accurate and versatile alternative to rK39 ICTs and aspirate microscopy.

Research topics

Research on Leishmaniasis Studies
Trypanosoma species research and implications
Leptospirosis research and findings

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DOI: 10.1371/journal.pntd.0011637

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