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article · Alzheimer s & Dementia

Significant association between <i>SCN8A</i> and Alzheimer disease in Puerto Ricans

2025Open accessUniversity of Ibadan

Abstract

Meta-analysis in the PR population identified a novel genome-wide significant locus. eHiCA identified several potential target genes at this novel locus, including SCN8A. Differential chromatin interactions between EU and AF ancestries may contribute to the significant admixture mapping signal.

Research topics

  • Genetic Associations and Epidemiology
  • Alzheimer's disease research and treatments
  • Forensic and Genetic Research

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DOI: 10.1002/alz70855_098248

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