article · IBRO Neuroscience Reports
Malathion, is an organophosphate pesticide (OP) commonly used in agriculture, industry, and veterinary medicine. Sex is a crucial factor in responding to neurotoxicants yet the sex-specific effects of OP exposure, particularly neurological impairments following chronic low-level exposure, remains limited. Our study aims to evaluate the neurobehavioral effects of developmental exposure to malathion, and uncover the different vulnerabilities observed across sexes. Pregnant mice were exposed to a low oral dose of malathion from gestation onset up to weaning of the pups, that were individually gavaged with a similar dose regimen until PND70.
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DOI: 10.1016/j.ibneur.2023.08.029
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