book chapter · BENTHAM SCIENCE PUBLISHERS eBooks
Schistosomiasis, a neglected tropical disease, affects millions worldwide. Treatment and control strategies rely entirely on the single drug praziquantel (PZQ), making the prospect of resistance emergence worrisome. The pressing need to introduce new antischistosomal agents necessitates exploring and repurposing chemotherapeutic history besides designing novel leads. In this context, this chapter summarizes the parasite life cycle, its clinical manifestations, and the progress in schistosomiasis chemotherapy with an overview of the validated drug targets, the emergence of drug resistance, and vaccination trials.
This page summarises published work. The authoritative version sits with the publisher.
DOI: 10.2174/9789815324785125010008
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