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review · Acta Neurologica Belgica

Safety and efficacy of extended versus standard interval dosing of natalizumab in multiple sclerosis patients: a systematic review and meta-analysis

202410 citationsOpen accessAlexandria University

Abstract

In summary, our meta-analysis indicates that natalizumab maintains its effectiveness under extended interval dosing [up to 8 weeks], presenting comparable risks for clinical relapses, MRI lesions, EDSS, and PML. Caution is advised given study limitations and heterogeneity. Robust conclusions necessitate well-designed high-quality prospective studies.

Research topics

  • Polyomavirus and related diseases
  • Multiple Sclerosis Research Studies
  • Mycobacterium research and diagnosis

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DOI: 10.1007/s13760-024-02480-6

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