article · Neurochemical Research

Roflumilast Elicits Therapeutic and Neuroprotective Effects in 3-Nitropropionic Acid-Induced Huntington’s Disease-Like Neurodegeneration in Rats by Mitigating NLRP3 Inflammasome-Mediated Pyroptosis, Ferroptosis, and Glial Activation

Mohamed Taha
D. H. Ben Salah
Kareem Abdou
Mahmoud A. Senousy

2026Open accessCairo University

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Research topics

Inflammasome and immune disorders
Tryptophan and brain disorders
Genetic Neurodegenerative Diseases

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DOI: 10.1007/s11064-026-04682-1

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