Recurrent Epithelial–Myoepithelial Carcinoma of the Submandibular Gland

Abstract

Epithelial-myoepithelial carcinoma (EMC) is a rare low-grade malignant tumor of the salivary glands. It occurs mostly in the parotid gland and is classically characterized by bilayered duct-like structures in histological examination. Its differential diagnosis includes all primary salivary gland clear cells tumors, and metastasis from renal cell carcinoma. The complete surgical resection with adjacent lymph nodes dissection represents the recommended therapy to ovoid recurrence. In our case, we describe a 37-year-old woman who presented a local recurrence of a submandibular tumor. The clinical examination demonstrated a well-circumscribed submandibular nodule. A surgical excision was performed and the histological immunohistochemical examination confirmed the diagnosis of submandibular EMC. The patient received a radiotherapy treatment and remained disease-free.