article · Bioorganic Chemistry

Rationally designed quinazolinone derivatives incorporating acetyl pyridine and thiazole scaffolds as dual EGFR/HER-2 anticancer agents: integrated biological evaluation, molecular profiling, and advanced computational studies

Hagar S. El-Hema
Modather F. Hussein
Eman S. Nossier
Mohammed F. Hamza
Rasha A.-S. El-Ghorab
Mohamed A. Hawata
Ahmed T. Elhendawy
Adel A.-H. Abdel-Rahman

2026Al-Azhar University

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Research topics

HER2/EGFR in Cancer Research
Quinazolinone synthesis and applications
Lung Cancer Treatments and Mutations

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DOI: 10.1016/j.bioorg.2026.110052

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