article · Bioorganic Chemistry

Rational design and synthesis of pyrazole-based sulfonamides as dual carbonic anhydrase and PRAK-targeting anticancer agents

Mariam M. Fakhry
Andrea Ammara
Paola Gratteri
Jalloul Bouajila
Mahmoud Abdelrahman Alkabbani
Mohamed Fares
Claudiu T Supuran
Mohamed A.Said
Alessandro Bonardi
Hatem A. Abdel-Aziz
Noha Zeidan
Sahar M. Abou-Seri

2026Egyptian Russian University

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Research topics

Enzyme function and inhibition
Phosphodiesterase function and regulation
Polyamine Metabolism and Applications

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DOI: 10.1016/j.bioorg.2026.110170

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