article · East and Central African Journal of Pharmaceutical Sciences
In Tanzania, essential medicines like amoxicillin, ciprofloxacin, metronidazole, and albendazole face potential quality challenges due to the risk of substandard and falsified drugs in the market. This study was carried out in Mwanza town, Tanzania to assess the quality of these drugs in order to address concerns about antimicrobial resistance and public safety. For this purpose, physical parameters, assay, and dissolution tests were conducted on samples of various brands according to the USP and BP monographs. All samples met USP standards for physical parameters and assay. But one brand of amoxicillin suspension failed assay test. Ciprofloxacin met dissolution criteria, but only one albendazole sample complied. About 47.6% of samples failed the quality tests performed. These results provide vital insights into pharmaceutical quality, safety and efficacy in the study area.
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DOI: 10.4314/ecajps.v25i3.3
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