article · Journal of Pharmacology and Experimental Therapeutics

Purmorphamine mitigates 3-nitropropionic acid-induced neurodegeneration via enhancing the BDNF/Akt/GSK-3β Signaling and attenuation of oxidative/nitrosative stress, neuroinflammation, and apoptosis

Mohamed Z. Habib
Mohamed Elshaer
Sherif A. Kamar
Moataz Kamel
Sara Elsayed Abdelrahman
Mohammed R. Rabei
Nourhan Ahmad Moussa
Ahmed M. Salama
Yasmin M. Aboul-Ela
Nouran K. Olama
Rania M. Hadhoud
Mohamed Osama Mostafa
Esraa M. Elnahas

2026Beni Suef University

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Research topics

Nerve injury and regeneration
Neuroinflammation and Neurodegeneration Mechanisms
NF-κB Signaling Pathways

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DOI: 10.1016/j.jpet.2026.104958

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