article · Tropical Medicine and Health

Progression from uncomplicated to severe malaria among children in settings receiving different combinations of malaria control interventions in sub-Saharan Africa: a systematic review and meta-analysis

Erick Jacob Okek
Benson Musinguzi
Obondo James Sande
Juliet Asio
Julius J. Lutwama (4427176)
Moses Ocan
Doare Kirsty Le
Jeshua Jehopio
Felix Bongomin
Silvia Awor
Annet Kinengyere Alison
Jonathan Kayondo

2026Open accessMakerere University

Abstract

In comparison to single or no intervention, combination of multiple malaria control interventions significantly protects against severe malaria, parasitaemia, gametocytes and uncomplicated malaria. In comparison to single or no interventions, deployment of multiple combinations of control interventions did not offer additional protection against progression from uncomplicated to severe malaria.

Research topics

Malaria Research and Control
Parasites and Host Interactions
Mosquito-borne diseases and control

Sustainable Development Goals

Good Health and Well-being

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DOI: 10.1186/s41182-026-00938-2

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