PROGNOSTIC SIGNIFICANCE OF GLYCATED HEMOGLOBIN LEVEL IN PATIENTS UNDERGOING PRIMARY PERCUTANEOUS CORONARY INTERVENTION

Abstract

Introduction: Diabetes is a common comorbidity among patients hospitalized with ACS, with a rising prevalence over the previous 10 years and a high mortality rate. Approximately 25% of patients with STEMI have a history of diabetes, whereas over 40% have undiagnosed T2DM or pre-diabetes. patients who have ASCVD, AF, or HF should be tested for diabetes, especially if they were admitted with an acute event. People who have stress hyperglycemia—defined as elevated blood sugar levels during hospitalization with a normal HbA1c—should also get post-discharge glucose assessment, to exclude prolonged abnormal glucose metabolism. Regardless of diabetes status, STEMI patients presented with hyperglycemia on admission have higher mortality rate than STEMI patients without hyperglycemia, there is a stronger correlation between blood glucose levels and mortality than between the prevalence of diabetes, Therefore, it is highly advised that all subjects have their blood glucose levels checked as soon as possible.Aim: The aim of this study is to assess the prognostic value of admission HbA1C level in patients undergoing primary PCI in Alexandria University Hospitals, on outcome of primary PCI and major adverse cardiovascular and cerebrovascular events.