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article · PLoS ONE

Prevalence, perceptions and factors associated with non-adherence to hepatotoxicity monitoring among people living with HIV on tuberculosis preventive treatment at Mulago ISS clinic

2026Open accessMakerere University

Abstract

The prevalence of non-adherence to hepatotoxicity monitoring was high within this pharmacovigilance sentinel site, given its clinical importance in HIV care and clear recommendations in the national HIV treatment guidelines. Health authorities should implement policies promoting hepatotoxicity monitoring in pharmacovigilance sentinel sites, especially for patients receiving secondary TPT, and allocate resources to support this initiative.

Research topics

  • Drug-Induced Hepatotoxicity and Protection
  • Tuberculosis Research and Epidemiology
  • Hepatitis C virus research

Sustainable Development Goals

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DOI: 10.1371/journal.pone.0345662

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