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review · Malaria Journal

Prevalence of Plasmodium falciparum plasmepsin2/3 gene duplication in Africa and Asia: a systematic review and meta-analysis

20251 citationOpen accessHubert Kairuki University

Abstract

The present review provides up-to-date evidence on the pfpm2/3 gene amplification. A substantial pooled proportion of pfpm2/3 gene amplification was reported, and many of the amplifications were observed in isolates from Asia rather than Africa. This calls for further efforts to monitor/control the emergence and spread of partner drug resistance in the regions to avoid the emergence of total ACT resistance, which will compromise global efforts toward eliminating malaria.

Research topics

  • Malaria Research and Control
  • Diverse Scientific Research Studies
  • Mosquito-borne diseases and control

Sustainable Development Goals

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DOI: 10.1186/s12936-025-05423-5

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