article · BMC Pregnancy and Childbirth
Hypertensive disorders during pregnancy remain a leading cause of perinatal death, making timely diagnosis and management essential for both mother and child. A retrospective review evaluated medical records from 241 preeclamptic women admitted and delivered at Woldia General Hospital in Ethiopia between 2011 and 2016. Overall, nearly 20 out of every 100 neonates born to preeclamptic mothers died, with a significantly higher proportion of deaths occurring in cases of severe preeclampsia compared to mild cases. Stillbirths formed the majority of these perinatal deaths, exceeding pre-discharge early neonatal fatalities. Magnesium sulphate was administered to prevent convulsions in over two thirds of the patients, showing an increasing trend of use across the study period. A maternal admission diastolic blood pressure above 110 mmHg was linked to a nearly threefold increase in perinatal mortality compared to lower readings.
Preeclampsia presents severe risks to newborn survival, particularly in low-resource clinical settings. Demonstrating the close connection between admission blood pressure levels, disease severity, and high perinatal death rates provides healthcare workers with clear indicators to prioritise urgent care. Understanding these clinical patterns helps hospitals improve triage protocols and maternal management to reduce preventable infant deaths.
The abstract does not indicate a direct commercial application pathway, as it reports retrospective observational clinical data rather than a new technology or product. However, the identified risk factors could inform clinical protocol design or decision-support software for hospital triage in maternal care settings.
AI-generated from the published abstract. Always read the original work before citing.
BACKGROUND: Hypertensive disorders of pregnancy are among the most common causes of perinatal death. The disorders are highly linked to multiple factors that make prediction and prevention challenging. Early diagnosis and proper management play a crucial role in the wellbeing and life of the women and her baby. In this study, we aimed to assess the association between different management options of preeclampsia and perinatal death at a public hospital in Ethiopia. METHODS: A document review was conducted on 241 preeclamptic patients' medical files who have been admitted and delivered in Woldia General Hospital from 2011 to 2016. The study was conducted from August 8 - September 10, 2017 in the aforementioned public hospital in Woldia town, Ethiopia. Associations were tested using Pearson chi squared test and binary logistic regression with a p-value < 0.05 considered significant. RESULT: In this study, nearly 20 every 100 neonates from preeclamptic women has been died and the figure was higher (76.59% Vs 23.4%) among neonates from severe preeclamptic women than mild preeclamptic women (p = 0.01). More than two thirds of the patients (69.3%) received magnesium sulfate to prevent convulsion. Perinatal death among women with diastolic blood pressures greater than 110 mmHg at admission was nearly 3 times (Adjusted Odds Ratio (AOR) = 2.824; 95% Confidence Interval (CI) (1.154-6.038)) higher compared to women with diastolic blood pressures below 110 mmHg. CONCLUSION: In the 5-year period, the magnitude of perinatal death among inpatient preeclamptic women was remarkably high and of which stillbirths exceeded pre-discharge early neonatal death. Utilization of magnesium sulfate tended to increase across years. Maternal diastolic blood pressure at admission was significantly associated with perinatal death.
This page summarises published work. The authoritative version sits with the publisher.
DOI: 10.1186/s12884-020-02909-9
Is something wrong with this record? Report it or request removal.
Discussion
Have you built on this work, tried to replicate it, or seen it applied in practice? Share what you know. Verified researchers and MARATTO™ domain experts can open a discussion, and any member can reply. Contributions are reviewed before they appear.
No discussion yet. Open the first thread.
New to MARATTO™? Create a free account.
