Predictors of Early Variceal Rebleeding after Endoscopic Therapy in Cirrhotic Patients

Abstract

Background: The management of cirrhotic patients experiencing variceal bleeding focuses on controlling the hemorrhage and preventing early rebleeding and mortality. Local risk factors, such as an HVPG above 12 mmHg, the size of the varices, and the presence of warning signs during endoscopy, are key predictors for early variceal rebleeding.Aim: The work aimed predict risk factors for early variceal rebleeding after endoscopic therapy.Methods: In this prospective study, 184 patients were enrolled from the endoscopy unit at Tanta University Hospital's Tropical Medicine and Infectious Diseases Department in Egypt. The study's duration was 5 months, encompassing both recruitment and follow-up.Results: The results of the multivariate logistic regression analysis indicated that a Child-Pugh score of ≥10, MELD score ≥16, presence of fundal varices, serum creatinine and INR were independent predictors for 5-days rebleeding.Conclusions: Child-Pugh score, MELD score, serum creatinine, INR and fundal varices are independent risk factors for 5-day rebleeding.