article · Bioorganic Chemistry

Precise structure manipulation of selective estrogen receptor modulators led to first-in-class thiophene-3-benzamide derivatives as potential ER-antagonists without uterotrophic activity

Bader Huwaimel
Hamdoon A. Mohammed
Nader M Alrashidi
Marwan A Alrashidi
Rakan E. Alshammari
Amr S. Abouzied
Abdul‐Hamid Emwas
Saad Alqarni
Mohamed K. S. El‐Nagar
Al‐Shaimaa F. Ahmed
Abdulelah Y Albladi
Shaymaa E. Kassab

2025University of Sadat City

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Research topics

Estrogen and related hormone effects
Nuclear Receptors and Signaling
Retinoids in leukemia and cellular processes

Sustainable Development Goals

2Zero Hunger

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DOI: 10.1016/j.bioorg.2025.108512

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