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review · World Journal of Gastrointestinal Surgery

Pancreatic pseudocyst: The past, the present, and the future

202422 citationsOpen accessZagazig University

In plain language

This review summarises current knowledge on pancreatic pseudocysts, which are encapsulated fluid collections with an inflammatory wall that develop at least four weeks after pancreatitis. Patients often present with non-specific abdominal pain. Diagnosis is typically confirmed using contrast-enhanced computed tomography or magnetic resonance imaging, with endoscopic ultrasound and fluid analysis used for diagnostic uncertainty. Pseudocysts can lead to complications such as haemorrhage, infection, or rupture. Management strategies, including endoscopic or surgical drainage, are determined by the presence of symptoms and complications like biliary or gastric outlet obstruction. The review discusses the evolution of definitions, diagnostic methods, and treatment approaches for this condition.

Key takeaways

  • Pancreatic pseudocysts are encapsulated fluid collections with inflammatory walls, diagnosed at least four weeks after pancreatitis onset.
  • Diagnosis involves imaging like contrast-enhanced CT or MRI, with endoscopic ultrasound used for uncertain cases.
  • Potential complications of pancreatic pseudocysts include haemorrhage, infection, and rupture.
  • Management strategies, such as endoscopic or surgical drainage, are guided by symptoms and complications like obstruction.

Why it matters

This review helps medical professionals understand the current best practices for identifying and treating pancreatic pseudocysts, a common complication of pancreatitis. Improved understanding of this condition can lead to more effective patient care and better health outcomes for those affected.

Commercialisation angle

The abstract describes a review of an existing medical condition and its management, and does not indicate an application pathway for new products or services.

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Abstract

A pancreatic pseudocyst is defined as an encapsulated fluid collection with a well-defined inflammatory wall with minimal or no necrosis. The diagnosis cannot be made prior to 4 wk after the onset of pancreatitis. The clinical presentation is often nonspecific, with abdominal pain being the most common symptom. If a diagnosis is suspected, contrast-enhanced computed tomography and/or magnetic resonance imaging are performed to confirm the diagnosis and assess the characteristics of the pseudocyst. Endoscopic ultrasound with cyst fluid analysis can be performed in cases of diagnostic uncertainty. Pseudocyst of the pancreas can lead to complications such as hemorrhage, infection, and rupture. The management of pancreatic pseudocysts depends on the presence of symptoms and the development of complications, such as biliary or gastric outlet obstruction. Management options include endoscopic or surgical drainage. The aim of this review was to summarize the current literature on pancreatic pseudocysts and discuss the evolution of the definitions, diagnosis, and management of this condition.

Research topics

  • Pancreatitis Pathology and Treatment
  • Gastrointestinal disorders and treatments
  • Pancreatic and Hepatic Oncology Research

Sustainable Development Goals

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This page summarises published work. The authoritative version sits with the publisher.

DOI: 10.4240/wjgs.v16.i7.1986

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