P1268 Impact of religion fasting on the condition of Inflammatory Bowel Disease: primary results of a multicenter multinational study

Abstract

Abstract Background The religion fasting is classified as a form of intermittent fasting, closely resembling time-restricted feeding protocols that typically last 12–16 hours daily. It has recently gained significant scientific interest due to its potential health benefits, particularly its anti-inflammatory effects. The current study aims to evaluate relation between religion fasting and IBD condition as a multi factorial disorder. Methods during a 6 months’ period, IBD cases who attend in IBD outpatient clinics of 15 referral centers of 8 countries requested to fill a questionnaire about their experience regarding religion fasting and then results compared between those who taking fasting and other IBD cases without fasting. Results overall 536 cases evaluated including 286 cases of UC and 214 cases with CD (270 males (50.4%)), average age 37.1 y. Among them 61.8% (331 cases) had experience of religion fasting. The most prevalent reasons for not to try fasting include fear of disease flare or exacerbation during fasting (52.4%), no believe in fasting (30.9%) and fear of change in pattern of medicine consumption (23.2%). Among those who took fasting, 69.8% changed the pattern and time of their medicine consumption during fasting and 12% has stopped to consume their medications. 27.4% of them experienced disease exacerbation or flare during fasting, 9.1% used to be admitted to hospital due to sever flare and 21.3% had exacerbation of diarrhea or bleeding during or immediately after fasting. 64.6% of patients consulted with their physician or caregiver before fasting about eligibility to take fasting while 35.3% consulted with non-medical persons. Conclusion overall religion fasting is not dangerous for IBD patients and most of IBD patients do not experience disease flare or exacerbation after fasting. They should encourage to consult with their physician before fasting to avoid any undesirable event or disease exacerbation during or immediately after fasting. Conflict of interest: Alavi Nejad, Pezhman: None to declare Ebrahimi Daryani, Nasser: none to declare Ramezani, Elmira: none to declare Sadeq Merzah Al-Turaihi, Dhurgham: none to declare Farhan, Nawal: none to declare Abdulkareem Abdullah, Muntadher: none to declare Zaky, Samy: none to declare Abdullah, Muhammad: none to declare Rangga Pribadi, Rabinnu: none to declare Sattar Abdulqader, Harem: none to declare Hussien, Mohammed: no Bane, Abate: none to declare Assefa, Kaleb: none to declare Alhalabi`, Marouf: none to declare Abdelnaby, Hassan Ba: none to declare Yousry Soliman, Moataz: none Lak, Elena: none Raja Ali, Affendi: none Bazdar, Monireh: none Soleymani, Maral: none Mohammed Mahros, Aya: none to declare Rezaei, Mohamad Javad: none Emara, Mohammed: none Abdelaziz, Mohamed Ahmed: NO CONFLICTS OF INTEREST