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article · Expert Opinion on Pharmacotherapy

Oral anticoagulation with versus without antiplatelet therapy in patients with stable coronary artery disease and an indication for anticoagulation: a meta-analysis with trial sequential analysis

Abstract

In patients with stable CAD requiring OAC, OAC monotherapy significantly reduces bleeding and improves net clinical benefit without increasing ischemic risk. These findings support OAC monotherapy, particularly with DOACs, as the preferred long-term strategy, especially in East Asian populations.

Research topics

  • Atrial Fibrillation Management and Outcomes
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Venous Thromboembolism Diagnosis and Management

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DOI: 10.1080/14656566.2025.2610371

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