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article · BMC Complementary Medicine and Therapies

Optimization of in vivo antimalarial efficacy of combinations of aqueous leaf extracts of Artemisia annua L., Vernonia amygdalina Del, and Microglossa pyrifolia (Lam.) Kuntze using factorial design

20242 citationsOpen accessUniversity of Jos

Abstract

An optimum combination of the three plants as a natural herbal antimalarial therapy was obtained using factorial design, and it offers an alternative to first line Artemisinin based Combination Therapy (ACTs) as parasite resistance looms. This combination could be further developed into a standard phytopharmaceutical and subjected to Randomized Controlled Trials (RCTs).

Research topics

  • Drug-Induced Hepatotoxicity and Protection
  • Natural Antidiabetic Agents Studies
  • Ethnobotanical and Medicinal Plants Studies

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DOI: 10.1186/s12906-024-04691-z

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