article · International Immunopharmacology

Okra seed polysaccharides mitigate neuroinflammation and cognitive impairment via modulation of Nrf2/HO-1, HMGB1/RAGE/TLR4/NF-κB, NLRP3/Caspase-1, JAK-2/STAT-3, AMPK/SIRT1/m-TOR, PI3K/AKT/CREB/BDNF/TrkB and PERK/CHOP/Bcl-2 axes

Jilan A. Nazeam
Ahmed M. Atwa
Ian Black
Varughese A. Mulamoottil
Hala M. El-Hefnawy
Karema Abu‐Elfotuh
Riham A. El‐Shiekh
Shaimaa M Hafez
Nabil M. Selim
Ehsan Khedre Mohamed
Ayah M. H. Gowifel
Ahmed M. Hamdan
Parastoo Azadi

20256 citationsModern University for Information and Technology

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Research topics

Medicinal Plants and Neuroprotection
Advances in Cucurbitaceae Research
Medicinal Plant Research

Sustainable Development Goals

2Zero Hunger

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DOI: 10.1016/j.intimp.2025.114110

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