(O-05) Sexual Dysfunction and Serum Prolactin Level in a Sample of Patients with Methamphetamine Dependence in Eastern Province in Saudi Arabia: A Cross-sectional Study

Abstract

Abstract Background Methamphetamine usage has become more widespread, which is a global societal concern. Drug-related vulnerable behavior can be avoided with the help of drug use data. The incidence and characteristics of sexual dysfunction are not well understood among Saudi patients, despite the fact that it is widely prevalent among methamphetamine abusers. The aim of this cross-sectional comparative investigation was to test the relationship between male’s dependent on methamphetamine and sexual dysfunctions in Erada Complex in Dammam, Saudi Arabia. Methods 124 participants were involved in this work. The evaluation was conducted using a questionnaire designed for demographic information, two scales (Arabic version of SCID-I and the international index of erectile Function-Arabic version) and a measurement of prolactin level for patients who were hospitalized in order to distinguish among cases of dependency on methamphetamine and normal healthy control. Results One hundred twenty-four male participants were involved in this study with mean age of 32.81 ± 6.51 years. They were consisting of 44.35% of controls and 55.65% of patients. 47 males from the cases group (68.12%) were having erectile dysfunction while, only 19 males (34.55%) from the control group were complaining from erectile dysfunction. The patients who had erectile dysfunction were divided into four categories which were 36.17% (Mild), 38.3% (Mild to moderate), 14.89% (moderate) and 10.64% (severe). There was a significant negative correlation between prolactin levels and scores of erectile function among cases group. Conclusion Erectile function was significantly impacted by methamphetamine addiction in tested group of male Saudi patients, according to the investigation's current findings. There was a significant negative correlation between erectile function scores and levels of prolactin. There is an urgency to reduce harm through proper sexual behavior instruction, rehabilitation for addiction, and substance abuse prevention.