article · RSC Advances

Novel NHC-based Pd–PEPPSI complexes: synthesis, structural characterization by X-ray diffraction, biological properties, and catalytic performance in <i>N</i> -alkylation reactions

Lamia Boubakri
Jamil Kraı̈em
Sabri Hassen
Harald Kelm
Anis Attour
Youssef Arfaoui
İsmail Özdemir
Nevin Gürbüz
Naceur Hamdi

2026Open accessUniversity of Tunis El Manar

Abstract

. We emphasize that all palladium-NHC-PEPPSI complexes are efficient compounds against bacteria and fungi as potential antimicrobial agents. In addition, the anticancer activity of these compounds was determined. Higher cytotoxicity relative to cisplatin was observed across all tested cell lines.

Research topics

Asymmetric Hydrogenation and Catalysis
Organoboron and organosilicon chemistry
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry

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DOI: 10.1039/d6ra00146g

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