article · Future Medicinal Chemistry

Novel isatin conjugates endowed with analgesic and anti-inflammatory properties: design, synthesis and biological evaluation

LaVauria D. Brown
Rajnish Kumar
Rajeev Sakhuja
Nermin Samir
Jade T. Moore
S. Patel
Adel S. Girgis
Mona F. Said
Anurag T. K. Baidya
Anshuman Khadanga
Siva S. Panda

20245 citationsOpen accessAin Shams University

Abstract

Compound <b>4c</b> emerged as a promising lead candidate for developing safer and more effective anti-inflammatory and analgesic agents. Its robust efficacy, safety profile, and computational validation highlight its potential for further optimization in therapeutic applications.

Research topics

Computational Drug Discovery Methods
Cancer therapeutics and mechanisms
Synthesis and biological activity

Sustainable Development Goals

Zero Hunger

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DOI: 10.1080/17568919.2024.2437981

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