Neuromeningeal Tuberculosis (TNM): Study of 24 Cases Covering Clinical, Paraclinical, Therapeutic and Progressive Aspects

Abstract

This study aims to analyse the epidemiological, clinical, paraclinical, therapeutic and evolving aspects of neuromeningeal tuberculosis (TNM) through a retrospective study of 21 patients hospitalized between January 2019 and December 2023 in the infectious diseases department of the Rabat military hospital. The average age at diagnosis was 49.5 years, with a predominance in the age group of 20 to 40 years (47.61%). The average time to diagnosis was 25 days. Initial symptoms were generally general signs (100%), followed by headache (61.90%), vomiting (47.61%) and motor deficits (33.33%). All patients underwent lumbar puncture and brain CT scan. Anti-bacillary treatment and corticosteroid therapy were administered to all participants. The outcome was favorable in 61.90% of cases, fatal in 9.52%, and marked by neurological sequelae in 28.57%.