article · Systematic Reviews
This protocol outlines a systematic review and meta-analysis focused on neonatal mortality in Ethiopia. The study aims to determine the extent, causes, and contributing factors of newborn deaths, which remain a significant public health challenge despite overall reductions in under-five mortality. Researchers will conduct a thorough search across various electronic databases and grey literature, with two independent reviewers screening and extracting data. Study quality will be assessed using the Newcastle-Ottawa Scale. The collected data will be analysed using STATA 11 software to provide pooled estimates and identify determinants of neonatal mortality. The findings are expected to offer up-to-date knowledge to inform health policy and research efforts in Ethiopia.
Understanding the specific causes and factors contributing to neonatal deaths in Ethiopia is crucial for developing effective interventions. This systematic review will consolidate existing evidence, providing a clear picture of the problem. This knowledge can guide public health strategies and resource allocation to reduce preventable newborn deaths, ultimately saving lives and improving child health outcomes.
This research is a protocol for a systematic review, which is an early-stage research activity. It aims to synthesise existing evidence to inform health policy and research, rather than developing a direct commercial product or service. The abstract does not indicate an application pathway for commercialisation.
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BACKGROUND: A child's risk of dying is highest in the neonatal period, i.e. the first 28 days of life. Newborn death accounts for nearly half of under-five death. More than 80% of newborn deaths are the result of preventable and treatable conditions. Ethiopia has made significant progress towards reducing under-five mortality; however, the rate of neonatal mortality (NMR) still accounts for 41% of under-five deaths. With this systematic review and meta-analysis, we aim to determine the magnitude, causes, and determinants of neonatal mortality in Ethiopia. METHODS: We will conduct a comprehensive search of the following electronic databases: PubMed, MEDLINE, EMBASE, CINAHL, Google Scholar, and maternity and infant care databases as well as grey literature. We will assess the quality of studies by using Newcastle-Ottawa Scale (NOS) checklist. Two reviewers will screen all retrieved articles, conduct data extraction, and then critically appraise all identified studies. We will analyse data by using STATA 11 statistical software. We will demonstrate pooled estimates and determinants of neonatal mortality with effect size and 95% confidence interval. DISCUSSION: The result from this systematic review will inform and guide health policy planners and researchers on the burden, causes, and determinants of neonatal mortality in Ethiopia. To our knowledge, this is the first systematic review in Ethiopia. We will synthesise the findings to generate up-to-date knowledge on neonatal mortality in Ethiopia. SYSTEMATIC REVIEW REGISTRATION: PROSPERO-CRD42018099663.
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DOI: 10.1186/s13643-019-1012-x
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