article · RSC Advances

Molecular docking and <i>in vivo</i>/<i>in vitro</i> studies of a novel thiadiazole Schiff base as a hepatoprotective drug against angiogenesis induced by breast cancer

Norah F. Alqahtani
Reda F.M. Elshaarawy
Serag Eldin I. Elbehairi
Heba W. Alhamdi
Ali Shati A
Mohammad Y. Alfaifi
Waleed M. Serag
Abdulrahman M. Saleh
Ebtesam S. Kotb
Yasser A. Hassan

20246 citationsOpen accessDelta University for Science and Technology

Abstract

, respectively. These stronger interactions involved H-bonding, ionic bonds, and hydrophobic π-interactions. Overall, TISSB2 can be a promising therapeutic option for the treatment of EAC-induced tumour angiogenesis.

Research topics

Synthesis and Characterization of Heterocyclic Compounds
Synthesis and biological activity
Synthesis of Tetrazole Derivatives

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DOI: 10.1039/d4ra06398h

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