article · Naunyn-Schmiedeberg s Archives of Pharmacology

Modulation of AMPK/SIRT1 signaling by piribedil attenuates cyclophosphamide-induced nephrotoxicity via PI3K/Akt, MAPKs, and TLR4/NLRP3 pathways with regulation of KIM-1/NGAL

Ahmed M. El-Dessouki
Tarek A. Yousef
Sahar K. Ali
Arwa Omar Al Khatib
Bassant M. Barakat
Asmaa Ramadan
Nada A. Ashour
Mohamed N. Goda
Mashael A. Alghamdi
Ahmed A. Al-Karmalawy

2026Delta University for Science and Technology

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Research topics

Chemotherapy-induced organ toxicity mitigation
Sirtuins and Resveratrol in Medicine
Drug-Induced Hepatotoxicity and Protection

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1007/s00210-025-04909-y

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