article · Science and Technology Nexus
Objective This review aims to highlight the biological characteristics of mesenchymal stem cells (MSCs) and their derived exosomes, focusing on their therapeutic roles in liver diseases and cancer. Material and Methods A comprehensive literature review was conducted to evaluate MSC sources, isolation methods, and the biological functions of MSC-derived exosomes. Relevant experimental and clinical studies addressing their mechanisms of action in liver pathology and cancer were analysed. Results MSCs and their exosomes demonstrated significant potential in modulating immune responses, reducing inflammation and fibrosis, promoting hepatocyte regeneration, and influencing the tumour microenvironment. MSC-derived exosomes also showed advantages as cell-free therapeutic agents and targeted drug delivery systems due to their low immunogenicity and biological stability. Conclusion MSCs and MSC-derived exosomes represent promising therapeutic platforms for regenerative medicine and cancer treatment, with strong potential for future clinical translation.
This page summarises published work. The authoritative version sits with the publisher.
DOI: 10.25259/stn_26_2025
Is something wrong with this record? Report it or request removal.
Discussion
Have you built on this work, tried to replicate it, or seen it applied in practice? Share what you know. Verified researchers and MARATTO™ domain experts can open a discussion, and any member can reply. Contributions are reviewed before they appear.
No discussion yet. Open the first thread.
New to MARATTO™? Create a free account.
