article · Asian Pacific Journal of Cancer Prevention

LncRNA ANRIL Promotes Glucose Metabolism and Proliferation of Colon Cancer in a High-Glucose Environment and is Associated with Worse Outcome in Diabetic Colon Cancer Patients

20245 citationsOpen accessZagazig University

Abstract

A high-glucose environment can increase the tumor-promoting effect of ANRIL. ANRIL can promote glucose metabolism and colon cancer proliferation by downregulating miR-186-5p with subsequent upregulation of glycolysis enzymes expression and inhibition of apoptosis.

Research topics

Cancer-related molecular mechanisms research
Metabolism, Diabetes, and Cancer
Gastric Cancer Management and Outcomes

Sustainable Development Goals

Zero Hunger

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DOI: 10.31557/apjcp.2024.25.4.1371

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