Isolation and Antibiotic Sensitivity of Klebsiella pneumoniae among Urinary Tract Infected Patients in Dalhatu Araf Specialist Hospital Lafia, Nasarawa State Nigeria

Abstract

Background and Objectives: Klebsiella pneumoniae complications with limited therapeutic options is considered as one major health issues concerning healthcare professionals worldwide. It is one of the leading nosocomial bacterial pathogen that causes most urinary tract infection, and recently the antibiotic resistance of Klebsiella pneumonia has totally increased dramatically. Cross-sectional study was performed from September 2021 to the end of December 2021. This aimed at the isolation and antibiotic sensitivity of the Klebsiella pneumoniae among patients with signs and symptoms of UTI.
 Materials and Methods: Cross- sectional study was performed from September 2021 to the end of December 2021. About120 urine specimens collected were analysed to detect the presence of Klebsiella pneumoniae. The Disc diffusion method was used to determine the antibiotic sensitivity pattern of the isolates.
 Results: Of the 120 specimens collected, only 72 (60%) produced growth. The sensitivity test revealed that all the isolates were sensitive to levofloxacin, 30 isolates (14.2%) were sensitive to ciprofloxacin, 28 isolates (13.2%) were sensitive to gentamycin, 20 isolates (9.4%) were sensitive to travid, while Augmentin has the sensitivity of 17 (8.1%). It revealed that levofloxacin has the lowest resistance of 0 (0%) while travid has the highest resistance of 15(21.7%).
 Conclusion: The antibiotic sensitivity pattern of the isolate revealed that all the isolates were completely sensitive to levofloxacin and more resistant to Augmentin and travid.